Total Enteral Nutrition Facilitates Wound Healing Through Preventing Intestinal Atrophy, Keeping Protein Anabolism and Suppressing Inflammation

“In this study, wound healing was faster in TEN group than in TPN group, in spite of equivalent body weight changes after burn. There were few original articles to demonstrate superiority of TEN to TPN in wound healing using rat model [16-18]. Judging from data of nitrogen accounts and prices in this experiment, TEN can direct more anabolic state than TPN, although total protein, albumin, transferrin were equivalent between TPN and TEN group. In addition, blood urea nitrogen (BUN) that is one of protein metabolites was lower in TEN than in TPN in our study. TPN treated malnourished rats gained more weight with greater body fat formation than TEN group but had lower nitrogen [19]. Thus, our results and a previous report suggest that TEN may facilitate wound healing by maintaining protein anabolism more than TPN.”