Novel Use of Doxycycline in Continuous-Instillation Negative Pressure Wound Therapy as “Wound Chemotherapy”

From Foot and Ankle Specialist…

Abstract Only
Negative-pressure wound therapy (NPWT) is frequently employed in the treatment of complex wounds. The authors present a description of real-time streaming therapy of a variety of wound chemotherapeutic agents through NPWT. Doxycycline, which acts as a competitive inhibitor of matrix metalloproteinases and tumor necrosis factor alpha and further decreases inflammation [...]

Expert Insights On Dispensing Wound Care Products In The Office

Dispensing wound care products in the office can facilitate patient convenience, patient adherence and a better continuity of care that fosters improved outcomes. Accordingly, this author provides an overview of products that could be dispensed to patients in the office as well as insights on inventory management, coding and reimbursement.

Is High Pressure Better Than Low Pressure For NPWT?

From Podiatry Today…
Over a decade ago, Fleischmann, Morykwas and their respective colleagues first introduced negative pressure wound therapy (NPWT).1,2 Their early work confirmed the effectiveness of NPWT in enhancing healing in both human and animal models.
Fleischmann and colleagues used NPWT in combination with antiseptic solutions in 27 orthopedic wounds and were able to obtain a [...]

A Closer Look At Ultrasonic Debridement

Can ultrasonic debridement facilitate improved wound healing? Sharing insights from their clinical experience as well as the literature, these authors discuss the mechanism of ultrasonic debridement, how it compares to other debridement methods and offer perspectives on the advantages and weaknesses of ultrasonic debridement.

Combating The Impact Of Oxygen Free Radicals On DFU Healing

From Podiatry Today…
For those with diabetes, careful management of blood sugar is imperative to prevent any number of complications, including those that contribute to poor wound healing, which is so common in diabetes.
One such problem is the development of foot ulcers, which reportedly affects 15 percent of individuals with diabetes.1,2 Diabetic foot ulcers are significant [...]

Making Room For Nerve Decompression In The Diabetic Limb Salvage Armamentarium

From Podiatry Today…
I read with interest the recent article on diabetic limb salvage (“How To Form A Diabetic Limb Salvage Team” in the June 2010 issue). Over the last 14 years, I have been significantly involved with wound care and limb salvage in the diabetic patient population. In 1998, I was asked to join the [...]